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AboutPricing
Disease ReportsDepressive disorder
MeSH D003866 - depressive disorder
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Competitive Landscape
Events Timeline
Commercial
Clinical Trials
Competitive landscape
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D019964:Mood disorders
67 Companies
4 Drugs
$
Success rate
D003866: 
Depressive disorder
166 Companies
41 Drugs
$
Success rate
D000088323:Vascular depression
0 Companies
0 Drugs
Success rate
D003865:Major depressive disorder
78 Companies
14 Drugs
$
Success rate
D016574:Seasonal affective disorder
1 Company
1 Drug
$
Success rate
D019052:Postpartum depression
2 Companies
2 Drugs
$
Success rate
D019263:Dysthymic disorder
4 Companies
1 Drug
$
Success rate
D061218:Treatment-resistant depressive disorder
1 Company
1 Drug
$
Success rate
D065446:Premenstrual dysphoric disorder
0 Companies
0 Drugs
Success rate
Events Timeline
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Commercial
Company Name
Drug Name
Trade Name
Patent Expires
Approval Date
Revenue
Period
TevaAlprazolam Alprazolam  1994-07-29   
Amitriptyline Amitriptyline  1982-01-01   
Buspirone Buspirone  2002-02-28   
Clomipramine Clomipramine  1997-04-04   
Doxepin Doxepin  1987-11-09   
Fluvoxamine Fluvoxamine  2002-09-10   
Imipramine Imipramine  1982-01-01   
Methylphenidate Methylphenidate  2012-07-19   
Mirtazapine Mirtazapine  2003-01-24   
Nefazodone Nefazodone  2003-09-16   
Nortriptyline Nortriptyline  1996-04-11   
Paliperidone Paliperidone  2021-07-06   
Paroxetine Paroxetine  2007-06-29   
Amitriptyline, Perphenazine Perphenazine Amitriptyline  1986-09-11   
Pramipexole Pramipexole Teva  2008-12-18   
Sertraline Sertraline  2006-06-30   
Trazodone Trazodone  1987-12-11   
Venlafaxine Venlafaxine  2010-06-28   
Protriptyline Vivactil  1982-01-01   
Trimipramine Surmontil  1982-01-01   
Novast LaboratoriesDesipramine Desipramine  2017-12-26   
Pramipexole Pramipexole  2022-02-03   
Taro PharmaceuticalCitalopram Citalopram  2006-03-22   
Clomipramine Clomipramine  1996-12-31   
Doxepin Doxepin  2020-07-01   
Nortriptyline Nortriptyline  2000-05-08   
Glenmark PharmaceuticalsCitalopram Citalopram  2009-02-27   
Lithium Lithium  2009-02-03   
Pramipexole Pramipexole  2010-10-08   
MylanAlprazolam Alprazolam  1993-10-19   
Buspirone Buspirone  2001-03-28   
Amitriptyline, Chlordiazepoxide Chlordiazepoxide Amitriptyline  1986-12-10   
Citalopram Citalopram  2004-11-05   
Clomipramine Clomipramine  1998-04-30   
Doxepin Doxepin  1986-05-13   
Fluvoxamine Fluvoxamine  2001-10-15   
Lithium carbonate Lithium  2002-06-27   
Methylphenidate Methylphenidate  2022-03-14   
Mirtazapine Mirtazapine  2003-06-19   
Paroxetine hydrochloride, Paroxetine Paroxetine  2004-03-08   
Amitriptyline, Perphenazine Perphenazine Amitriptyline  1988-11-10   
Sertraline Sertraline  2007-03-20   
Trazodone Trazodone  2009-06-02   
Venlafaxine Venlafaxine  2008-06-13   
Doxepin Zonalon  1994-04-01   
Rising PharmaceuticalsBupropion Bupropion  2010-05-03   
Nortriptyline Nortriptyline  1993-07-26   
Imipramine Imipramine Pamoate  2013-06-28   
Lorazepam Lorazepam  1998-07-23   
Methylphenidate Methylphenidate  2016-11-07   
Pramipexole Pramipexole  2018-10-03   
Selegiline Selegiline  2019-04-02   
Trazodone Trazodone  1990-04-30   
Amitriptyline Amitriptyline  2023-05-19   
Buspirone Buspirone  2002-03-19   
Quagen PharmaMethylphenidate Methylphenidate  2020-06-04   
Selegiline Eldepryl  1996-05-15   
Fluvoxamine Fluvoxamine  2000-11-29   
Selegiline Selegiline  1989-06-05   
Sertraline Sertraline  2008-01-31   
NATCO PharmaPramipexole Pramipexole  2010-10-08   
Trazodone Trazodone  1991-02-27   
Alprazolam Alprazolam  2015-04-15   
Citalopram Citalopram  2008-04-10   
Johnson & JohnsonPaliperidone Byannli (previously Paliperidone Janssen-Cilag International)  2020-06-18   
Methylphenidate Concerta  2000-08-01 $612 M Q2/24-Q1/25 
Paliperidone Invega  2006-12-19 $4,067 M Q2/24-Q1/25 
Paliperidone Invega Hafyera 2036-04-05 2015-05-18   
Paliperidone Invega Sustenna 2031-01-26 2009-07-31   
Esketamine Spravato  2019-12-18 $1,171 M Q2/24-Q1/25 
Paliperidone Trevicta (previously Paliperidone Janssen)  2014-12-05   
Paliperidone Xeplion  2011-03-04   
GSKBupropion Wellbutrin  1985-12-30   
Bupropion Zyban  1997-05-14   
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Clinical Trials
Historical Success Rate
Phase 1
69%
18/26
Phase 2
46%
18/39
Phase 3
82%
50/61
Approved: 34Overall Success rate: 26%
All Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Company name
Phase 1
Phase 2
Phase 3
Phase 4
Drug Name
Teva
Alprazolam,
Buspirone,
Buspirone hydrochloride,
Fluvoxamine,
Methylphenidate,
Methylphenidate hydrochloride,
Mirtazapine,
Paroxetine,
Paroxetine hydrochloride,
Pramipexole,
Sertraline,
Venlafaxine
Mylan
Sertraline,
Lithium carbonate,
Venlafaxine,
Alprazolam,
Citalopram,
Paroxetine,
Paroxetine hydrochloride,
Esreboxetine,
Reboxetine,
Napaea dioica whole
Johnson & Johnson
Paliperidone,
Esketamine,
Methylphenidate,
Methylphenidate hydrochloride,
Paliperidone palmitate,
Benzodiazepine,
Escitalopram,
Seltorexant,
Sirukumab,
Doconexent,
Zopiclone,
Aspartame,
Aticaprant,
Toludesvenlafaxine,
Napaea dioica whole,
R228060,
Fmx101,
Sominex
GSK
Bupropion,
Bupropion hydrochloride,
Losmapimod,
Benzodiazepine,
Escitalopram,
Benzocaine,
Enoblituzumab,
Casopitant,
Edrecolomab,
Icosapent,
Doconexent,
Aspartame,
Bevifimod,
Lotamilast,
ORVEPITANT,
RADAFAXINE,
Remetinostat,
Riboprine,
Usistapide,
VERUCERFONT,
VESTIPITANT,
NS-2359,
Napaea dioica whole,
GSK-356278,
Wellbutrinxl,
Histone-arginine methyltransferase carm1,
Buproprion,
GSK163090,
Isoxaflutole,
Nicoderm
Roche
Escitalopram,
Basimglurant,
Aspartame,
DECOGLURANT
Cipla
Citalopram,
Escitalopram,
Dexpramipexole,
Histone-arginine methyltransferase carm1,
Surlorian
Lupin Research
Bupropion,
Bupropion hydrochloride
Sandoz
Alprazolam,
Bupropion,
Bupropion hydrochloride,
Clomipramine,
Imipramine,
Pramipexole
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