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Disease ReportsDepressive disorder
MeSH D003866 - depressive disorder
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Commercial
Clinical Trials
Competitive landscape
D019964:Mood disorders
$
Success rate
D003866: 
Depressive disorder
D000088323:Vascular depression
0 Companies
0 Drugs
Success rate
D003865:Major depressive disorder
D016574:Seasonal affective disorder
$
Success rate
D019052:Postpartum depression
$
Success rate
D019263:Dysthymic disorder
$
Success rate
D061218:Treatment-resistant depressive disorder
$
Success rate
D065446:Premenstrual dysphoric disorder
0 Companies
0 Drugs
Success rate
Events Timeline
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Commercial
Company Name
Drug Name
Trade Name
Patent Expires
Approval Date
Revenue
Period
TevaAlprazolam Alprazolam  1994-07-29   
Amitriptyline Amitriptyline  1982-01-01   
Buspirone Buspirone  2002-02-28   
Clomipramine Clomipramine  1997-04-04   
Doxepin Doxepin  1987-11-09   
Fluvoxamine Fluvoxamine  2002-09-10   
Imipramine Imipramine  1982-01-01   
Methylphenidate Methylphenidate  2012-07-19   
Mirtazapine Mirtazapine  2003-01-24   
Nefazodone Nefazodone  2003-09-16   
Nortriptyline Nortriptyline  1996-04-11   
Paliperidone Paliperidone  2021-07-06   
Paroxetine Paroxetine  2007-06-29   
Amitriptyline, Perphenazine Perphenazine Amitriptyline  1986-09-11   
Pramipexole Pramipexole Teva  2008-12-18   
Sertraline Sertraline  2006-06-30   
Trazodone Trazodone  1987-12-11   
Venlafaxine Venlafaxine  2010-06-28   
Protriptyline Vivactil  1982-01-01   
Novast LaboratoriesDesipramine Desipramine  2017-12-26   
Pramipexole Pramipexole  2022-02-03   
Taro PharmaceuticalCitalopram Citalopram  2006-03-22   
Clomipramine Clomipramine  1996-12-31   
Doxepin Doxepin  2020-07-01   
Nortriptyline Nortriptyline  2000-05-08   
Glenmark PharmaceuticalsCitalopram Citalopram  2009-02-27   
Lithium Lithium  2009-02-03   
Pramipexole Pramipexole  2010-10-08   
MylanAlprazolam Alprazolam  1993-10-19   
Buspirone Buspirone  2001-03-28   
Amitriptyline, Chlordiazepoxide Chlordiazepoxide Amitriptyline  1986-12-10   
Citalopram Citalopram  2004-11-05   
Clomipramine Clomipramine  1998-04-30   
Doxepin Doxepin  1986-05-13   
Fluvoxamine Fluvoxamine  2000-11-29   
Lithium Lithium  2002-06-27   
Methylphenidate Methylphenidate  2022-03-14   
Mirtazapine Mirtazapine  2003-06-19   
Paroxetine Paroxetine  2004-03-08   
Amitriptyline, Perphenazine Perphenazine Amitriptyline  1988-11-10   
Sertraline Sertraline  2007-03-20   
Trazodone Trazodone  2009-06-02   
Venlafaxine Venlafaxine  2008-06-13   
Doxepin Zonalon  1994-04-01   
Rising PharmaceuticalsBupropion Bupropion  2010-05-03   
Nortriptyline Nortriptyline  1993-07-26   
Imipramine Imipramine Pamoate  2013-06-28   
Lorazepam Lorazepam  1998-07-23   
Methylphenidate Methylphenidate  2016-11-07   
Pramipexole Pramipexole  2018-10-03   
Selegiline Selegiline  2019-04-02   
Trazodone Trazodone  1990-04-30   
Amitriptyline Amitriptyline  2023-05-19   
Buspirone Buspirone  2002-03-19   
NATCO PharmaPramipexole Pramipexole  2010-10-08   
Trazodone Trazodone  1991-02-27   
Alprazolam Alprazolam  2015-04-15   
Citalopram Citalopram  2008-04-10   
Johnson & JohnsonPaliperidone Byannli (previously Paliperidone Janssen-Cilag International)  2020-06-18   
Methylphenidate Concerta  2000-08-01 $664 M Q4/23-Q3/24 
Paliperidone Invega  2006-12-19 $4,170 M Q4/23-Q3/24 
Paliperidone Invega Hafyera 2036-04-05 2015-05-18   
Paliperidone Invega Sustenna 2031-01-26 2009-07-31   
Esketamine Spravato  2019-12-18 $963 M Q3/23-Q3/24 
Paliperidone Trevicta (previously Paliperidone Janssen)  2014-12-05   
Paliperidone Xeplion  2011-03-04   
GSKBupropion Wellbutrin  1985-12-30   
Bupropion Zyban  1997-05-14   
RocheAmitriptyline Endep  1982-01-01   
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Clinical Trials
Historical Success Rate
Phase 1
69%
18/26
Phase 2
46%
18/39
Phase 3
82%
50/61
Approved: 34Overall Success rate: 26%
All Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Company name
Phase 1
Phase 2
Phase 3
Phase 4
Drug Name
Abbott Biotherapeutics
AbbVie
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6
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