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AboutPricing
Disease ReportsDepressive disorder
MeSH D003866 - depressive disorder
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Competitive Landscape
Events Timeline
Commercial
Clinical Trials
Competitive landscape
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D019964:Mood disorders
59 Companies
3 Drugs
$
Success rate
D003866: 
Depressive disorder
166 Companies
36 Drugs
$
Success rate
D000088323:Vascular depression
0 Companies
0 Drugs
Success rate
D003865:Major depressive disorder
80 Companies
13 Drugs
$
Success rate
D016574:Seasonal affective disorder
1 Company
1 Drug
$
Success rate
D019052:Postpartum depression
2 Companies
2 Drugs
$
Success rate
D019263:Dysthymic disorder
4 Companies
1 Drug
$
Success rate
D061218:Treatment-resistant depressive disorder
1 Company
1 Drug
$
Success rate
D065446:Premenstrual dysphoric disorder
0 Companies
0 Drugs
Success rate
Events Timeline
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Commercial
Company Name
Drug Name
Trade Name
Patent Expires
Approval Date
Revenue
Period
TevaAlprazolam Alprazolam  1994-07-29   
Amitriptyline Amitriptyline  1982-01-01   
Buspirone Buspirone  2002-02-28   
Clomipramine Clomipramine  1997-04-04   
Doxepin Doxepin  1987-11-09   
Fluvoxamine Fluvoxamine  2002-09-10   
Imipramine Imipramine  1982-01-01   
Methylphenidate Methylphenidate  2012-07-19   
Mirtazapine Mirtazapine  2003-01-24   
Nefazodone Nefazodone  2003-09-16   
Nortriptyline Nortriptyline  1996-04-11   
Paliperidone Paliperidone  2021-07-06   
Paroxetine Paroxetine  2007-06-29   
Amitriptyline, Perphenazine Perphenazine Amitriptyline  1986-09-11   
Pramipexole Pramipexole Teva  2008-12-18   
Sertraline Sertraline  2006-06-30   
Trazodone Trazodone  1987-12-11   
Venlafaxine Venlafaxine  2010-06-28   
Protriptyline Vivactil  1982-01-01   
Novast LaboratoriesDesipramine Desipramine  2017-12-26   
Pramipexole Pramipexole  2022-02-03   
Taro PharmaceuticalCitalopram Citalopram  2006-03-22   
Clomipramine Clomipramine  1996-12-31   
Doxepin Doxepin  2020-07-01   
Nortriptyline Nortriptyline  2000-05-08   
Glenmark PharmaceuticalsCitalopram Citalopram  2009-02-27   
Lithium Lithium  2009-02-03   
Pramipexole Pramipexole  2010-10-08   
MylanAlprazolam Alprazolam  1993-10-19   
Buspirone Buspirone  2001-03-28   
Amitriptyline, Chlordiazepoxide Chlordiazepoxide Amitriptyline  1986-12-10   
Citalopram Citalopram  2004-11-05   
Clomipramine Clomipramine  1998-04-30   
Doxepin Doxepin  1986-05-13   
Fluvoxamine Fluvoxamine  2000-11-29   
Lithium Lithium  2002-06-27   
Methylphenidate Methylphenidate  2022-03-14   
Mirtazapine Mirtazapine  2003-06-19   
Paroxetine Paroxetine  2004-03-08   
Amitriptyline, Perphenazine Perphenazine Amitriptyline  1988-11-10   
Sertraline Sertraline  2007-03-20   
Trazodone Trazodone  2009-06-02   
Venlafaxine Venlafaxine  2008-06-13   
Doxepin Zonalon  1994-04-01   
Rising PharmaceuticalsBupropion Bupropion  2010-05-03   
Nortriptyline Nortriptyline  1993-07-26   
Imipramine Imipramine Pamoate  2013-06-28   
Lorazepam Lorazepam  1998-07-23   
Methylphenidate Methylphenidate  2016-11-07   
Pramipexole Pramipexole  2018-10-03   
Selegiline Selegiline  2019-04-02   
Trazodone Trazodone  1990-04-30   
Amitriptyline Amitriptyline  2023-05-19   
Buspirone Buspirone  2002-03-19   
NATCO PharmaPramipexole Pramipexole  2010-10-08   
Trazodone Trazodone  1991-02-27   
Alprazolam Alprazolam  2015-04-15   
Citalopram Citalopram  2008-04-10   
Johnson & JohnsonPaliperidone Byannli (previously Paliperidone Janssen-Cilag International)  2020-06-18   
Methylphenidate Concerta  2000-08-01 $641 M Y2024 
Paliperidone Invega  2006-12-19 $4,222 M Y2024 
Paliperidone Invega Hafyera 2036-04-05 2015-05-18   
Paliperidone Invega Sustenna 2031-01-26 2009-07-31   
Esketamine Spravato  2019-12-18 $1,077 M Y2024 
Paliperidone Trevicta (previously Paliperidone Janssen)  2014-12-05   
Paliperidone Xeplion  2011-03-04   
GSKBupropion Wellbutrin  1985-12-30   
Bupropion Zyban  1997-05-14   
RocheAmitriptyline Endep  1982-01-01   
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Clinical Trials
Historical Success Rate
Phase 1
69%
18/26
Phase 2
46%
18/39
Phase 3
82%
50/61
Approved: 34Overall Success rate: 26%
All Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Company name
Phase 1
Phase 2
Phase 3
Phase 4
Drug Name
Teva
Sertraline,
Pramipexole,
Venlafaxine,
Amitriptyline,
Alprazolam,
Mirtazapine,
Buspirone,
Fluvoxamine,
Paroxetine,
Doconexent,
Wellbutrin
Mylan
Sertraline,
Lithium carbonate,
Venlafaxine,
Alprazolam,
Citalopram,
Lithium,
Paroxetine,
Esreboxetine,
Reboxetine,
Gladem
Johnson & Johnson
Paliperidone,
Esketamine,
Methylphenidate,
Escitalopram,
Seltorexant,
Sirukumab,
Esmirtazapine,
Doconexent,
Zopiclone,
Terfenadine,
Sodium chloride,
Aspartame,
Aticaprant,
Toludesvenlafaxine,
Ago178,
Gladem,
R228060,
Lexapro,
Fmx101,
Arm1,
Wellbutrin,
Arm2,
Mydfrin,
Sominex
GSK
Bupropion,
Losmapimod,
Escitalopram,
Benzocaine,
Vitamin e,
Enoblituzumab,
Casopitant,
Edrecolomab,
Icosapent,
Doconexent,
Alfacalcidol,
Aspartame,
Bevifimod,
ORVEPITANT,
RADAFAXINE,
Riboprine,
VERUCERFONT,
VESTIPITANT,
Retinol,
Lovaza,
NS2359,
Omacor,
Gladem,
GSK356278,
Lexapro,
Wellbutrinxl,
Catecholamines,
Arm1,
Buproprion,
Wellbutrin,
GSK163090,
GSK372475,
Nicoderm
Roche
Escitalopram,
Basimglurant,
Aspartame,
DECOGLURANT,
Lexapro
Cipla
Citalopram,
Escitalopram,
Dexpramipexole,
Lexapro,
Arm1,
Arm2
Lupin Research
Bupropion
Sandoz
Alprazolam,
Amitriptyline,
Bupropion,
Clomipramine,
Imipramine,
Pramipexole
Boehringer Ingelheim
Pramipexole,
Escitalopram,
Gladem,
Lexapro
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6
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